Synaptic, Cellular, and Systems Neuroscience

How do experiences become stable memories—and how do those circuits change in depression?

The Robinson Lab studies how coordinated groups of neurons build, stabilize, and communicate memories across brain circuits. As we prepare to launch in the Université de Montréal neuroscience community, we connect molecular and cellular mechanisms with neural dynamics and behavior.

Our approach

We investigate the hippocampal-prefrontal circuits that support memory reactivation and consolidation. By bridging synapses, cell types, neural assemblies, and behavior, we seek to understand why particular neurons join an experience-linked ensemble, how that ensemble persists, and how circuit dysfunction may contribute to depression-like behavior.

Research at a glance

Illustration accompanying Large sharp-wave ripples promote hippocampo-cortical memory reactivation and consolidation during sleep

Neuron · 2026

Large sharp-wave ripples promote hippocampo-cortical memory reactivation and consolidation during sleep.

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Illustration accompanying Top-down regulation of subcortical regions by hippocampal long-range inhibition

Current Biology · 2025

Top-down regulation of subcortical regions by hippocampal long-range inhibition.

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Science figure illustrating a hippocampal circuit mechanism to balance memory reactivation during sleep

Science · 2024

A hippocampal circuit mechanism to balance memory reactivation during sleep.

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Illustration accompanying selective memory encoding, routing, and replay

Neuron · 2023

Hippocampo-cortical circuits for selective memory encoding, routing, and replay.

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Illustration accompanying an adult-stage transcriptional program for survival of serotonergic connectivity

Cell Reports · 2022

An adult-stage transcriptional program for survival of serotonergic connectivity.

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Journal figure accompanying Neuregulin 1 and ErbB4 kinase regulation of hippocampal sharp wave ripples

Journal of Neuroscience · 2022

Neuregulin 1 and ErbB4 Kinase Actively Regulate Sharp Wave Ripples in the Hippocampus.

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Illustration accompanying Dynamic ErbB4 activity in hippocampal-prefrontal synchrony

Neuron · 2018

Dynamic ErbB4 Activity in Hippocampal-Prefrontal Synchrony and Top-Down Attention in Rodents.

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Illustration accompanying Large sharp-wave ripples promote hippocampo-cortical memory reactivation and consolidation during sleep

Neuron · 2026

Large sharp-wave ripples promote hippocampo-cortical memory reactivation and consolidation during sleep.

Read publication

Illustration accompanying Top-down regulation of subcortical regions by hippocampal long-range inhibition

Current Biology · 2025

Top-down regulation of subcortical regions by hippocampal long-range inhibition.

Read publication

Science figure illustrating a hippocampal circuit mechanism to balance memory reactivation during sleep

Science · 2024

A hippocampal circuit mechanism to balance memory reactivation during sleep.

Read publication

Illustration accompanying selective memory encoding, routing, and replay

Neuron · 2023

Hippocampo-cortical circuits for selective memory encoding, routing, and replay.

Read publication

Illustration accompanying an adult-stage transcriptional program for survival of serotonergic connectivity

Cell Reports · 2022

An adult-stage transcriptional program for survival of serotonergic connectivity.

Read publication

Journal figure accompanying Neuregulin 1 and ErbB4 kinase regulation of hippocampal sharp wave ripples

Journal of Neuroscience · 2022

Neuregulin 1 and ErbB4 Kinase Actively Regulate Sharp Wave Ripples in the Hippocampus.

Read publication

Illustration accompanying Dynamic ErbB4 activity in hippocampal-prefrontal synchrony

Neuron · 2018

Dynamic ErbB4 Activity in Hippocampal-Prefrontal Synchrony and Top-Down Attention in Rodents.

Read publication

Principal investigator

Heath Larsson Robinson, PhD

Founder and Principal Investigator

Dr. Robinson is a neuroscientist studying hippocampal circuits, sharp-wave ripples, memory reactivation, and long-range neural communication. He earned his PhD in Neuroscience from Case Western Reserve University and is currently a Postdoctoral Fellow in Cornell University’s Department of Neurobiology and Behavior.

Learn more about Dr. Robinson →